Polioencephalomalacia (PEM) is a morphological diagnosis of a lesion in the brain characterized by necrosis of gray matter of the cerebral cortex. However, the term is most often used to indicate a specific central nervous system disease in ruminants assumed to be caused by the disruption of normal thiamine metabolism. The pathological lesion polioencephalomalacia is not caused only by thiamine problems. Therefore, it is important in communications between pathologists practitioners, and producers that everyone realizes how the others are using the term. In some countries such as Great Britain and Australia, the term cerebrocortical necrosis is used instead of PEM.
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South Dakota State University
Copyright © 1993 South Dakota State University
Neiger, Regg, "Polioencephalomalacia" (1993). South Dakota Sheep Field Day Proceedings and Research Reports, 1993. 10.