Document Type
Plan B - Open Access
Award Date
2020
Degree Name
Master of Science (MS)
Department
Biology and Microbiology
First Advisor
Greg Heiberger
Abstract
Microglial cells play a significant role in defense of the brain. However, in certain disease states, their response can lead to inflammation that can be detrimental to the survival of brain cells and have harmful effects on a person’s brain activity. Currently, the treatment options for microglial induced neuroinflammation are relatively limited. Adiponectin has recently appeared as a potential moderator of neuroinflammation as well as a promoter of neuroprotection. Adiponectin is a naturally occurring cytokine that has been shown to play a role in a multitude of processes throughout the body including potential as a microglial induced neuroinflammation. Adiponectin’s role in reducing neuroinflammation and promoting neuroprotection is investigated in this review.
One sentence summary: This review investigates recent studies on microglial cells role in neuroinflammation and possible treatment options for microglial induced neuroinflammation.
Format
application/pdf
Number of Pages
23
Publisher
South Dakota State University
Rights
In Copyright - Educational Use Permitted
http://rightsstatements.org/vocab/InC-EDU/1.0/
Recommended Citation
Stadem, Nathan, "Role of Adiponectin in Neuroinflammation & Neuroprotection" (2020). Biology and Microbiology Graduate Students Plan B Research Projects. 18.
https://openprairie.sdstate.edu/biomicro_plan-b/18