Document Type

Plan B - Open Access

Award Date

2022

Degree Name

Master of Science (MS)

Department

Biology and Microbiology

First Advisor

Greg Heiberger

Abstract

Viral vector vaccines have recently risen to the forefront of vaccinology, but there are multiple factors that must be addressed before they achieve widespread approval and use. The concept of using viruses as vectors is not new, and numerous attempts to create vaccines that utilize virus vectors have been made in the past 25 years. Despite this, only one viral vector vaccine has gained full approval by the FDA. The goal of this review is to provide a comprehensive overview of the types of viral vector vaccines, production and purification methods, current and future viral vector vaccines, the issues and limitations of viral vector vaccines, and how they can be improved for future use.

Number of Pages

23

Publisher

South Dakota State University

Rights

© 2022 Jaden Marks

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