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Document Type

DNP - University Access Only

Award Date


Degree Name

Doctor of Nursing Practice (DNP)


Graduate Nursing

First Advisor

Victoria Britson


sepsis, sepsis bundle, sepsis bundle and emergency department, sepsis management, sepsis and time to antibiotic, sepsis and protocol, sepsis treatment, rural hospitals, and patient outcomes


Cost and mortality from sepsis is high and increasing. According to the Agency for Healthcare Research and Quality, sepsis was the most expensive ailment to treat, costing almost $24 billion in 2013. The aim of this project was to create and implement a sepsis screening tool and treatment protocol, based upon the Surviving Sepsis Campaign and Minnesota Hospital Association guidelines, that reduced time to evidence-based treatment. The setting was a rural, Midwestern critical access emergency room (ER), with the primary sample population consisting of the medical staff in the ER. A secondary population was the adult patients who were diagnosed with sepsis in the ER. An educational power point about sepsis was assigned to the facility nurses via the facility’s online continuing education portal. The facility physicians were involved in the creation and approval of the sepsis protocol. A pre- and post-implementation analysis was completed with a reduction in time to treatment measured by determining the times to antibiotics, times to fluids, and compliance with serum lactate measurement. The results showed a decrease in the average time to fluids, however this was not statistically significant. The average time to antibiotics actually increased from pre-implementation.

Library of Congress Subject Headings

Septicemia -- Treatment.
Septicemia -- Diagnosis.
Critical care medicine.


Includes bibliographical references



Number of Pages



South Dakota State University


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