Author

M. L. Halling

Document Type

Thesis - Open Access

Award Date

1967

Degree Name

Master of Science (MS)

Department

Bacteriology

Abstract

For many years people have equated arsenic or compounds containing arsenic with poison. Inorganic arsenic compounds are used as chemotherapeutic agents as well as poisons. Organic arsenicals were introduced at the start of this century launching modern chemotherapy. The introduction of antibiotics in the 1940’s virtually replaced organic arsenicals in chemotherapy. Solutions of inorganic arsenic compounds are used as tonics for animals and to finish animals for show. Because arsenicals are excreted by animals in much the same structure as they are consumed and arsenite prevents both putrefaction and growth, it is possible the decomposition of animal excreta will be inhibited. The decomposition of animal wastes is of interest to the laboratory and to the nation. Thus, this study was undertaken to determine if growth could be inhibited by either the feed additive 3-nitro-40hydroxyphenylarsonic acid or 3-nitro-4 hydroxyphenlarsine oxide. Enzyme investigations were made to determine whether these two arsenicals inhibited enzymes of the tricarboxylic acid cycle.

Library of Congress Subject Headings

Organoarsenic compounds
Enzymes

Format

application/pdf

Publisher

South Dakota State University

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