Thesis - Open Access
Master of Science (MS)
Health and Nutritional Sciences
ACL Bone Collegiate Density Rupture Subchondral
The purpose of this study was to determine whether anterior cruciate ligament (ACL) rupture and reconstruction would lead to any significant changes in subchondral bone at the proximal tibia within 1 to 5 years post-surgical repair. Fifteen individuals (3 male, 12 female), aged 18 to 29 years old, who had sustained an ACL rupture and subsequent repair within the last 5 years were recruited for this study. An age and sexmatched control was recruited to match each participant. Subchondral volumetric bone mineral density (vBMD) of the proximal tibia was measured using peripheral quantitative computed tomography (pQCT). Additionally, jump force and efficiency were measured using a portable force plate as a means of determining muscle function. Total vBMD of the injured leg was greater in cases (276 ± 9 mg/cm3) versus controls (231 ± 10 mg/cm3) (P = 0.04). Total vBMD of the uninjured leg was not different between cases (256 ± 6 mg/cm3) and controls (239 ± 6 mg/cm3). All evaluated jump force and power values showed no significant difference between injured and uninjured legs in either the cases or the control group. Based on the results of this present study, we concluded that significant changes in subchondral bone could be seen within 1-5 years following ACL injury and reconstruction which may place injured individuals at a greater risk of developing posttraumatic osteoarthritis later in life. Future studies must be performed to determine the mechanism that is causing these changes in an effort to prevent problems later in life.
Number of Pages
South Dakota State University
In Copyright - Educational Use Permitted
Harbaugh, Zach, "The Impact of Anterior Cruciate Ligament Ruptures on Subchondral Bone Density in Collegiate Populations" (2020). Electronic Theses and Dissertations. 3915.