Title

The Relationship Between Shear Rate and Flow‐mediated Dilation is Altered by Acute Exercise

Document Type

Article

Publication Date

1-2012

Abstract

Aim: Endothelial function is a predictor of cardiovascular health and is improved with exercise training . However, it is not clear how exercise acutely affects endothelial function. Previous studies present conflicting results, resulting from varied exercise protocols and ambiguity in data analysis after exercise. The aims of this study were to compare brachial artery endothelial function at rest and post-exercise in and to compare the data expressed as a percent change and normalized to shear rate (SR).
Methods: Fifteen young, healthy subjects completed flow-mediated dila- tion (FMD) tests at rest and immediately after a continuous 30-min tread- mill exercise session. Flow-mediated dilation was calculated as perce nt change in diameter and also normalized for SR. Conclusion: The weak relationship in FMD and SR after exercise suggests that these data should not be normalized following aerobic exercise. Thus, endothelial function was attenuated after a continuous 30-min aerobic exercise session.

Publication Title

Acta Physiologica

Volume

205

First Page

394

Last Page

402

DOI of Published Version

10.1111/j.1748-1716.2012.02417.x

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