The problem of selenium poisoning has been known for many years, but the mechanism by which this element exerts its toxicity has not been clarified. As a result, what control measures are now available are of an empirical nature, and they fail to the give the most desirable protection. In search of a better control mechanism, the role of compounds containing biologically active methyl groups has been studied. Some experimental work indicated that these types of compounds might indeed be involved in the metabolism of selenium. However, not all workers’ data were in agreement, and it was felt that further studies were needed.
South Dakota State University
Olson, O.E.; Carlson, C.W.; and Lettis, Eriks, "Methionine and Related Compounds and Selenium Poisoning" (1958). Agricultural Experiment Station Technical Bulletins (1939-2011). 31.