Thesis - Open Access
Master of Science (MS)
It has been repeatedly verified that selenium, when fed as sodium selenite or sodium selenite, or injected intravenously or intraperitoneally, is chemically bound to the protein in various tissues. Further, it has been shown that selenium can be incorporated into protein in such organisms as yeast and bacteria, or even more complex organisms such as rats, dogs, and mice. It is the intent of this author to explore the role of a non-enzymatic reaction between the amino acids and selenium. Reports by previous investigators indicate that further work in this area is needed. Rosenfeld and Beath, and a number of other workers, reported finding selenium compounds in the various tissues of rats and dogs. Tests in the South Dakota State College Chemistry Laboratories indicate that selenium as selenite can be reduced to elemental selenium in an alkaline solution. Other workers have reported the formation of seleno-glutatione and seleno-cysteine from a non-enzymatic reaction of the amino acid or the tripeptide and sodium selentite. Thus it seemed that investigations along this line would prove fruitful.
Library of Congress Subject Headings
Selenium -- Physiological effect
Includes bibliographical references
Number of Pages
South Dakota State University
Miedema, Eddy, "Interaction of Selenite and Arsenite on Amino Acids and Related Compounds" (1961). Electronic Theses and Dissertations. 2778.