Document Type

Thesis - Open Access

Award Date


Degree Name

Master of Science (MS)

Department / School

Electrical Engineering and Computer Science

First Advisor

Sung Y. Shin


Brain MRI segmentation, Fuzzy C-Means, Local Binary Pattern


The segmentation of human brain Magnetic Resonance Image is an essential component in the computer-aided medical image processing research. Brain is one of the fields that are attracted to Magnetic Resonance Image segmentation because of its importance to human. Many algorithms have been developed over decades for brain Magnetic Resonance Image segmentation for diagnosing diseases, such as tumors, Alzheimer, and Schizophrenia. Fuzzy C-Means algorithm is one of the practical algorithms for brain Magnetic Resonance Image segmentation. However, Intensity Non- Uniformity problem in brain Magnetic Resonance Image is still challenging to existing Fuzzy C-Means algorithm. In this paper, we propose the Texture weighted Fuzzy C-Means algorithm performed with Local Binary Patterns on Three Orthogonal Planes. By incorporating texture constraints, Texture weighted Fuzzy C-Means could take into account more global image information. The proposed algorithm is divided into following stages: Volume of Interest is extracted by 3D skull stripping in the pre-processing stage. The initial Fuzzy C-Means clustering and Local Binary Patterns on Three Orthogonal Planes feature extraction are performed to extract and classify each cluster’s features. At the last stage, Fuzzy C-Means with texture constraints refines the result of initial Fuzzy C-Means. The proposed algorithm has been implemented to evaluate the performance of segmentation result with Dice’s coefficient and Tanimoto coefficient compared with the ground truth. The results show that the proposed algorithm has the better segmentation accuracy than existing Fuzzy C-Means models for brain Magnetic Resonance Image.

Library of Congress Subject Headings

Brain -- Magnetic resonance imaging.
Brain -- Imaging -- Analysis.
Fuzzy algorithms.


Includes bibliographical references



Number of Pages



South Dakota State University



Rights Statement

In Copyright