Dissertation - Open Access
Doctor of Philosophy (PhD)
Health and Nutritional Sciences
Pre-diabetes and type 2 diabetes (T2D) are significant public health challenges in the United States. Pre-diabetes and T2D are a multi-factorial disease characterized by genetic or environmental factors or a combination of both. There has been an upward trend over time in the prevalence of both pre-diabetes and T2D. Few epidemiological studies exist regarding the effect of baseline glycemic status on changes in body composition, bone health, and lipid profiles. To fill this critical gap, the purpose of this research was to examine both cross-sectional and longitudinal changes in glycemic status with changes in body composition, bone mass and density, and lipid profile and cardiovascular risk ratios in men aged 20 to 66 years. This dissertation uses data from the South Dakota Rural Bone Health Study, a population-based longitudinal study designed to investigate the impact of lifestyle factors on bone and body composition. Findings from this study provide insight into the adverse effect of changes in glycemic status on total and regional body composition and bone health. Creating prevention strategies targeted at individuals affected by, or at risk of, pre-diabetes and T2D, such as promoting a healthy diet, physical activity, and weight loss may reverse the unfavorable effects of pre-diabetes and T2D.
Number of Pages
South Dakota State University
In Copyright - Non-Commercial Use Permitted
Almusaylim, Khaleal, "Cross-Sectional and Longitudinal Effects of Glycemic Status on Body Composition, Bone, and Lipid Profile in Men Aged 20 to 66 Years: A Population-Based Study" (2019). Electronic Theses and Dissertations. 3169.
Available for download on Tuesday, April 21, 2020