Mary A. Anson

Document Type

Thesis - Open Access

Award Date


Degree Name

Master of Science (MS)

Department / School

Biology and Microbiology


Bovine ocular squamous cell carcinoma, commonly known as cancer eye, is a common and economically important problem to the U.S. cattle industry. This neoplasm is particularly significant in aged breeding stock. The tumor usually originates from the squamous epithelial cells of the corneal-scleral junction and the nicitating membrane of the eye. Eye cancer lesions progress from small pin point plaques to large tumors involving the eye and surrounding tissue. This disease causes parital or total loss of vision in the affected eye and the cancer may metastasize. The objectives of this research were to: investigate the properties of tumor cell cultures derived from bovine ocular squamous cell carcinoma and its precursor lesions, determine if viral agents are present in or can be induced in tumor cell cultures, and attempt to demonstrate viral antigens in the tumor cell cultures.

Library of Congress Subject Headings

Cattle -- Diseases

Virology -- Research

Eye -- Diseases



Number of Pages



South Dakota State University