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Document Type

Thesis - University Access Only

Award Date

1990

Degree Name

Master of Science (MS)

Department

Biology

First Advisor

David H. Francis

Abstract

Since its existence was first reported in 1977 by Konowalchuck et. al. (27), much has been done to characterize the properties of verotoxin produced by Escherichia coli. This toxin was distinguished from the classical heat-stable (ST) and heat-labile (LT) enterotoxins in that its toxic effect on Vero cells was irreversible, whereas the effect of LT and ST is reversible. Verotoxin (VT) has a subunit structure, isoelectric point and range of biological activities similar to that of Shiga toxin produced by Shigella dysenteriae type I (40).

Library of Congress Subject Headings

Verocytotoxins
Escherichia coli infections -- Pathogenesis
Enterotoxins
Immunosuppression

Format

application/pdf

Number of Pages

66

Publisher

South Dakota State University

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