Document Type


Publication Date



prrs, swine, respiratory disease, mystery swine disease (msd)

Extension Number

ExEx 11004


Veterinary and Biomedical Sciences


History A previously unrecognized disease of swine was first described in the United State in 1987. The condition was characterized by abortion, premature farrowing, stillborn and mummified pigs, and respiratory disease with death loss and chronic poor performance of nursing and weaned pigs. This disease was initially referred to as Mystery Swine Disease (MSD). As a result of research performed at South Dakota State University, the University of Minnesota, and the Central Veterinary Institute in the Netherlands, the condition became better characterized and was renamed Porcine Reproductive and Respiratory Syndrome (PRRS). PRRS continues to be a major cause of reproductive and respiratory disease of swine today.