Title

Disruption of Transepithelial Resistance by Enterotoxigenic Escherichia coli

Document Type

Article

Publication Date

2-2010

Keywords

bacterial pathogenesis, enterotoxigenic Escherichia coli, tight junction, transepithelial resistance

Abstract

Transepithelial resistance and tight junction protein localization in porcine intestinal epithelial cells were evaluated as a function of infection with porcine enterotoxigenicEscherichia coli isolates differing in adhesin and enterotoxin profiles. Robust heat-labile enterotoxin-independent reduction of host transepithelial resistance was observed in the absence of tight junction protein mislocalization.

Publication Title

Veterinary Microbiology

Volume

141

Issue

1-2

First Page

115

Last Page

119

DOI of Published Version

10.1016/j.vetmic.2009.08.020

Publisher

Elsevier

Rights

Copyright © 2010 Elseiver