Disruption of Transepithelial Resistance by Enterotoxigenic Escherichia coli
bacterial pathogenesis, enterotoxigenic Escherichia coli, tight junction, transepithelial resistance
Transepithelial resistance and tight junction protein localization in porcine intestinal epithelial cells were evaluated as a function of infection with porcine enterotoxigenicEscherichia coli isolates differing in adhesin and enterotoxin profiles. Robust heat-labile enterotoxin-independent reduction of host transepithelial resistance was observed in the absence of tight junction protein mislocalization.
DOI of Published Version
Copyright © 2010 Elseiver
Amber M. Johnson, Radhey S. Kaushik, Philip R. Hardwidge. (2010) Disruption of transepithelial resistance by enterotoxigenic Escherichia coli. Veterinary Microbiology. 141:115-119. DOI: 10.1016/j.vetmic.2009.08.020.