Pathogenesis of CTE: A Review of PTau, Lewy Bodies, and Cytokine Involvement in CTE

Author

Karter Keefer, South Dakota State University

Document Type

Plan B - Open Access

Award Date

2019

Degree Name

Master of Science (MS)

Department

Biology and Microbiology

First Advisor

Greg Heiberger

Abstract

Chronic Traumatic Encephalopathy (CTE) is a neuropathological disease that develops years after experiencing repetitive traumatic brain injuries. In recent years, this disease has been gaining recognition from professional, college, and high school teams that participate in contact sports. The purpose of this paper is to review available information about this neurodegenerative disease. Only limited published experiments are available on this disease. Research on CTE has been limited by the fact that patients can only be diagnosed with the disease by a post mortem autopsy. Many experiments were analyzed regarding different CTE pathologies, symptoms, and treatments. Articles used in this paper were restricted to only peer reviewed pieces. The outcome resulted in credible information about the disease, its neuropathy, and signs and symptoms, as well as possible treatment methods of the disease.

Format

application/pdf

Number of Pages

35

Publisher

South Dakota State University

Rights

Copyright © 2019 Karter Keefer

Recommended Citation

Keefer, Karter, "Pathogenesis of CTE: A Review of PTau, Lewy Bodies, and Cytokine Involvement in CTE" (2019). Biology and Microbiology Graduate Students Plan B Research Projects. 11.
https://openprairie.sdstate.edu/biomicro_plan-b/11