Document Type

Plan B - Open Access

Award Date

2020

Degree Name

Master of Science (MS)

Department

Biology and Microbiology

First Advisor

Greg Heiberger

Abstract

Microglial cells play a significant role in defense of the brain. However, in certain disease states, their response can lead to inflammation that can be detrimental to the survival of brain cells and have harmful effects on a person’s brain activity. Currently, the treatment options for microglial induced neuroinflammation are relatively limited. Adiponectin has recently appeared as a potential moderator of neuroinflammation as well as a promoter of neuroprotection. Adiponectin is a naturally occurring cytokine that has been shown to play a role in a multitude of processes throughout the body including potential as a microglial induced neuroinflammation. Adiponectin’s role in reducing neuroinflammation and promoting neuroprotection is investigated in this review.

One sentence summary: This review investigates recent studies on microglial cells role in neuroinflammation and possible treatment options for microglial induced neuroinflammation.

Format

application/pdf

Number of Pages

23

Publisher

South Dakota State University

Rights

In Copyright - Educational Use Permitted
http://rightsstatements.org/vocab/InC-EDU/1.0/

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