Document Type
Plan B - Open Access
Award Date
2022
Degree Name
Master of Science (MS)
Department
Biology and Microbiology
First Advisor
Greg Heiberger
Abstract
Hepatic encephalopathy is a temporary decline in mental function that is often associated with liver disease and/or portal-systemic disease. Hepatic encephalopathy (HE) symptoms can range from minor cognitive declines to coma and are known to result from excess ammonia accumulations in the blood stream subsequent to liver failure. While HE is known to result from hepatobiliary disorder, many of the physiological process underlying its development and progression remain to be elucidated. Recent studies have identified neurological, metabolic, and microbiome changes implicated in the disease state of HE. In this review, the roles of traditional pharmaceutical interventions and newly developing understandings of the molecular biology underlying hepatic encephalopathy will be explored.
Number of Pages
20
Publisher
South Dakota State University
Rights
© 2022 Els Reuvekamp
Recommended Citation
Reuvekamp, Els, "Interrelationships of Systemic Changes in Hepatic Encephalopathy" (2022). Biology and Microbiology Graduate Students Plan B Research Projects. 36.
https://openprairie.sdstate.edu/biomicro_plan-b/36