Document Type
Plan B - Open Access
Award Date
2024
Degree Name
Master of Science (MS)
Department
Biology and Microbiology
First Advisor
Greg Heiberger
Abstract
The human gut contains trillions of bacteria that play a key role in gastric homeostasis. Commensal bacteria play a critical role in the formation of the gastrointestinal barrier that prevents invasion of other pathogenic bacteria and also serves as a secondary metabolism system that aids in the synthesis of dietary fibers into many essential nutrients such as vitamins, sugars, and especially short chain fatty acids (SCFAs) in the anaerobic conditions in the large intestine. These SCFAs assist in regulating immune tolerance to commensal bacteria of the gut and promote an anti-inflammatory state important to lowering the incidence of inflammatory disorders and diseases.
Publisher
South Dakota State University
Rights
© 2024 Caden Johnson
Recommended Citation
Johnson, Caden, "Regulation of Inflammatory Signaling by the Gut Microbiome" (2024). Biology and Microbiology Graduate Students Plan B Research Projects. 48.
https://openprairie.sdstate.edu/biomicro_plan-b/48