Characterization of Cell-Cell Interactions in Normal and tW32 Homozygous Preimplantation Mouse Embryos

Author

Phyllis M. Johnson

Document Type

Thesis - Open Access

Award Date

1976

Degree Name

Master of Science (MS)

Department / School

Biology

First Advisor

Nels H. Granholm

Abstract

Immediate objectives of the following studies were to characterize and compare normal versus lethal mutant (t^W32/t^W32) cellular interactions during preimplantation mouse development. Principal experimental methods used included embryo culture and microscopy. Control and mutant embryos were analyzed in vitro to identify chronological events and phenotypic characteristics of t^W32 homozygotes. Cell-cell associations of uncompacted and compacted 8-cell control (ICR) embryos were analyzed by quantitative electron microscopy. Lastly, light microscopic analyses were performed on control and mutant (t^W32/t^W32) morulae.

Library of Congress Subject Headings

Cell interaction
Embryology
Mice -- Anatomy

Format

application/pdf

Publisher

South Dakota State University

Recommended Citation

Johnson, Phyllis M., "Characterization of Cell-Cell Interactions in Normal and tW32 Homozygous Preimplantation Mouse Embryos" (1976). Electronic Theses and Dissertations. 5552.
https://openprairie.sdstate.edu/etd/5552