Observations on Attachment and Spreading of Zonaless tw32/tw32 (Brachyury Locus) and Control ICR Preimplantation Mouse Embryos

Author

Ker Hwa Tung

Document Type

Thesis - Open Access

Award Date

1978

Degree Name

Master of Science (MS)

Department / School

Biology

First Advisor

Nels H. Granholm

Abstract

The objective of the first part of this thesis is to test, in vitro, the adhesiveness of different stages of denuded preimplantation ICR mouse embryos for the substratum. In the second part, experiments are conducted to determine if there are differences in the attachment and spreading potential between t^w32 homozygotes and normal embryos. Studies by Spiegelman (1976), Calarco and Brown (1968), Granholm and Johnson (1978), and others indicate that t¹², t^w32 and other lethal t alleles of the Brachyury or T-complex may affect cell surface properties. Thus, the objectives of this thesis include the acquisition of cell surface data from mutant (t^w32/t^w32) as well as normal (ICR) preimplantation mouse embryos.

Library of Congress Subject Headings

Embryology
Mice -- Anatomy
Cell membranes

Format

application/pdf

Publisher

South Dakota State University

Recommended Citation

Tung, Ker Hwa, "Observations on Attachment and Spreading of Zonaless tw32/tw32 (Brachyury Locus) and Control ICR Preimplantation Mouse Embryos" (1978). Electronic Theses and Dissertations. 5635.
https://openprairie.sdstate.edu/etd/5635