Document Type

Plan B - Open Access

Award Date


Degree Name

Master of Science (MS)


Home Economics

First Advisor

Michael Crews


Diarrhea with associated malnutrition is the most common cause of life-threatening morbidity in infants reared in developing countries. Rehydration and the maintenance of adequate fluid and electrolyte balance is the key to the management of the child with acute diarrheal disease. The purpose of this project was to design a study for determining the effectiveness of a 'locally' produced oral rehydration therapy (ORT) that could be easily administered in the home. Thirty grams of whole ground corn in one liter of potable water was boiled for 20 minutes to produce a colloidal suspension which was cooled to 30°C. Three and half grams of Sodium chloride was then added. A stock suspension based on the above formula would have been prepared for the entire project. A minimum of 48 piglets divided into six treatment groups would have been used. Groups one through four will be the treatment groups while groups five and six will serve as controls. The efficacy of the ORT would be evaluated based on the abilities of the Transmissible gastroenteritis virus (TGE) inoculated piglets to recover from diarrhea. Consequently, the hydration status, acidosis state, electrolyte contents of the stools and plasma of these piglets and the prevalence of certain microorganisms would be monitored.



Number of Pages



South Dakota State University


Copyright © Alexander Azuka Nweji