Document Type
Thesis - University Access Only
Award Date
2001
Degree Name
Master of Science (MS)
Department / School
Biology and Microbiology
Abstract
The yellow mouse (AY/a) has long been associated with obesity and infertility caused by AY-induced excess agouti protein production. A mutation (mahogany, mg) has been found to suppress the obesity of yellow mice in mahogany yellow (mg/mg AY/a) mice. Reproductive parameters previously reported to be different in yellow and black (a/a) mice were studied in combination with the mahogany mutation in order to determine the effects of mahogany on fertility of mahogany black (mg/mg a/a) and mahogany yellow (mg/mg AY/a) mice. Data from this study suggest that mahogany significantly modifies or alters the normal progression of infertility in yellow mice with wild-type or normal alleles at the mahogany locus ( +/+ AY/a). In short, female mahogany yellow mice are significantly more fertile than age-matched yellow "controls". Although the mechanism of mahogany is not known, data from this study may allow us to identify and characterize interactions between two genetic foci that regulate a number of key metabolic processes.
Library of Congress Subject Headings
Mice -- Genetics
Mice -- Reproduction
Lethal mutation
Format
application/pdf
Number of Pages
129
Publisher
South Dakota State University
Recommended Citation
Oberg, Trynda N., "Effects of the Mahogany (mg) Mutation on Reproductive Parameters in Mice (Mus Musculus)" (2001). Electronic Theses and Dissertations. 820.
https://openprairie.sdstate.edu/etd2/820